35 Helpful Bible Verses About Despair

In the journey of life, we all encounter moments of despair—times when hope seems distant, and the weight of our circumstances feels overwhelming. Yet, even in our darkest hours, the pages of the Bible offer rays of light, guiding us with words of comfort, strength, and encouragement.

From the Psalms to the Epistles, the Scriptures abound with verses that speak directly to the depths of our despair, offering solace and pointing us toward the unshakeable hope found in God’s promises.

In this article, we will look into Bible verses about despair, exploring how these timeless truths can uplift our spirits, renew our faith, and anchor us in the midst of life’s storms. Do read on!

Top Bible Verses About Despair

Psalm 34:18

“The LORD is close to the brokenhearted and saves those who are crushed in spirit.”

Psalm 42:11

“Why, my soul, are you downcast? Why so disturbed within me? Put your hope in God, for I will yet praise him, my Savior and my God.”

Psalm 147:3

“He heals the brokenhearted and binds up their wounds.”

Isaiah 41:10

“So do not fear, for I am with you; do not be dismayed, for I am your God. I will strengthen you and help you; I will uphold you with my righteous right hand.”

Jeremiah 29:11

“For I know the plans I have for you,” declares the LORD, “plans to prosper you and not to harm you, plans to give you hope and a future.”

John 16:33

“I have told you these things, so that in me you may have peace. In this world you will have trouble. But take heart! I have overcome the world.”

Romans 8:28

“And we know that in all things God works for the good of those who love him, who have been called according to his purpose.”

2 Corinthians 4:8-9

“We are hard pressed on every side, but not crushed; perplexed, but not in despair; persecuted, but not abandoned; struck down, but not destroyed.”

Hebrews 13:5-6

“Keep your lives free from the love of money and be content with what you have, because God has said, ‘Never will I leave you; never will I forsake you.’ So we say with confidence, ‘The Lord is my helper; I will not be afraid. What can mere mortals do to me?’”

1 Peter 5:7

“Cast all your anxiety on him because he cares for you.”

Comfort in Times of Despair

Psalm 34:18

“The LORD is close to the brokenhearted and saves those who are crushed in spirit.”

Psalm 147:3

“He heals the brokenhearted and binds up their wounds.”

Matthew 11:28-29

“Come to me, all you who are weary and burdened, and I will give you rest. Take my yoke upon you and learn from me, for I am gentle and humble in heart, and you will find rest for your souls.”

2 Corinthians 1:3-4

“Praise be to the God and Father of our Lord Jesus Christ, the Father of compassion and the God of all comfort, who comforts us in all our troubles, so that we can comfort those in any trouble with the comfort we ourselves receive from God.”

Isaiah 41:10

“So do not fear, for I am with you; do not be dismayed, for I am your God. I will strengthen you and help you; I will uphold you with my righteous right hand.”

Hope Amidst Despair

Psalm 42:11

“Why, my soul, are you downcast? Why so disturbed within me? Put your hope in God, for I will yet praise him, my Savior and my God.”

Jeremiah 29:11

“For I know the plans I have for you,” declares the LORD, “plans to prosper you and not to harm you, plans to give you hope and a future.”

Romans 15:13

“May the God of hope fill you with all joy and peace as you trust in him, so that you may overflow with hope by the power of the Holy Spirit.”

Hebrews 6:19

“We have this hope as an anchor for the soul, firm and secure.”

Lamentations 3:21-23

“Yet this I call to mind and therefore I have hope: Because of the LORD’s great love we are not consumed, for his compassions never fail. They are new every morning; great is your faithfulness.”

Trusting God in Despair

Psalm 62:8

“Trust in him at all times, you people; pour out your hearts to him, for God is our refuge.”

Isaiah 26:3-4

“You will keep in perfect peace those whose minds are steadfast, because they trust in you. Trust in the LORD forever, for the LORD, the LORD himself, is the Rock eternal.”

Proverbs 3:5-6

“Trust in the LORD with all your heart and lean not on your own understanding; in all your ways submit to him, and he will make your paths straight.”

Psalm 56:3-4

“When I am afraid, I put my trust in you. In God, whose word I praise— in God I trust and am not afraid. What can mere mortals do to me?”

Romans 8:28

“And we know that in all things God works for the good of those who love him, who have been called according to his purpose.”

Finding Strength in Despair

Isaiah 40:31

“But those who hope in the LORD will renew their strength. They will soar on wings like eagles; they will run and not grow weary, they will walk and not be faint.”

Philippians 4:13

“I can do all this through him who gives me strength.”

2 Corinthians 12:9-10

“But he said to me, ‘My grace is sufficient for you, for my power is made perfect in weakness.’ Therefore I will boast all the more gladly about my weaknesses, so that Christ’s power may rest on me. That is why, for Christ’s sake, I delight in weaknesses, in insults, in hardships, in persecutions, in difficulties. For when I am weak, then I am strong.”

Ephesians 6:10

“Finally, be strong in the Lord and in his mighty power.”

Psalm 18:2

“The LORD is my rock, my fortress and my deliverer; my God is my rock, in whom I take refuge, my shield and the horn of my salvation, my stronghold.”

Perseverance Through Despair

Romans 5:3-5

“Not only so, but we also glory in our sufferings, because we know that suffering produces perseverance; perseverance, character; and character, hope. And hope does not put us to shame, because God’s love has been poured out into our hearts through the Holy Spirit, who has been given to us.”

James 1:12

“Blessed is the one who perseveres under trial because, having stood the test, that person will receive the crown of life that the Lord has promised to those who love him.”

Hebrews 10:35-36

“So do not throw away your confidence; it will be richly rewarded. You need to persevere so that when you have done the will of God, you will receive what he has promised.”

Galatians 6:9

“Let us not become weary in doing good, for at the proper time we will reap a harvest if we do not give up.”

2 Timothy 4:7

“I have fought the good fight, I have finished the race, I have kept the faith.”

Peace in the Midst of Despair

John 14:27

“Peace I leave with you; my peace I give you. I do not give to you as the world gives. Do not let your hearts be troubled and do not be afraid.”

Philippians 4:6-7

“Do not be anxious about anything, but in every situation, by prayer and petition, with thanksgiving, present your requests to God. And the peace of God, which transcends all understanding, will guard your hearts and your minds in Christ Jesus.”

Isaiah 26:3

“You will keep in perfect peace those whose minds are steadfast, because they trust in you.”

John 16:33

“I have told you these things, so that in me you may have peace. In this world you will have trouble. But take heart! I have overcome the world.”

Psalm 119:165

“Great peace have those who love your law, and nothing can make them stumble.”

Renewal and Restoration from Despair

Isaiah 40:29-31

“He gives strength to the weary and increases the power of the weak. Even youths grow tired and weary, and young men stumble and fall; but those who hope in the LORD will renew their strength. They will soar on wings like eagles; they will run and not grow weary, they will walk and not be faint.”

Psalm 51:10

“Create in me a pure heart, O God, and renew a steadfast spirit within me.”

2 Corinthians 4:16-18

“Therefore we do not lose heart. Though outwardly we are wasting away, yet inwardly we are being renewed day by day. For our light and momentary troubles are achieving for us an eternal glory that far outweighs them all. So we fix our eyes not on what is seen, but on what is unseen, since what is seen is temporary, but what is unseen is eternal.”

Lamentations 5:21

“Restore us to yourself, LORD, that we may return; renew our days as of old.”

Psalm 23:3

“He restores my soul. He leads me in paths of righteousness for his name’s sake.”

Encouragement in Times of Despair

Joshua 1:9

“Have I not commanded you? Be strong and courageous. Do not be afraid; do not be discouraged, for the LORD your God will be with you wherever you go.”

Psalm 27:14

“Wait for the LORD; be strong and take heart and wait for the LORD.”

Isaiah 41:13

“For I am the LORD your God who takes hold of your right hand and says to you, Do not fear; I will help you.”

1 Thessalonians 5:11

“Therefore encourage one another and build each other up, just as in fact you are doing.”

Romans 15:4

“For everything that was written in the past was written to teach us, so that through the endurance taught in the Scriptures and the encouragement they provide we might have hope.”

Faith Overcoming Despair

Hebrews 11:1

“Now faith is confidence in what we hope for and assurance about what we do not see.”

Matthew 17:20

“He replied, ‘Because you have so little faith. Truly I tell you, if you have faith as small as a mustard seed, you can say to this mountain, ‘Move from here to there,’ and it will move. Nothing will be impossible for you.’”

Mark 9:23

“‘If you can’?” said Jesus. “Everything is possible for one who believes.”

Romans 10:17

“So faith comes from hearing, and hearing through the word of Christ.”

Hebrews 11:6

“And without faith it is impossible to please God, because anyone who comes to him must believe that he exists and that he rewards those who earnestly seek him.”

Final Thought

In times of despair, turning to the promises of God offers a source of strength, comfort, and hope. By embracing faith over fear, trusting in God’s provision, finding solace in His presence, and overcoming doubt with belief, we can navigate through the darkest valleys with confidence. As students of His word, let us hold fast to these truths, knowing that God is faithful to fulfill His promises and carry us through every trial.

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